Ethyl 2-(Ethoxymethylene)-4,4,4-Trifluoroacetoacetate

Ethyl 2-(Ethoxymethylene)-4,4,4-Trifluoroacetoacetate - Names and Identifiers

Name	ethyl 2-(ethoxymethylene)-4,4,4-trifluoro-3-oxobu
Synonyms	ETHYL 3-ETHOXY-2-(2,2,2-TRIFLUOROACETYL)ACRYLATE ethyl 3-ethoxy-2-(2,2,2-trifluoroacetyl)acrylate ethyl 2-(ethoxymethylene)-4,4,4-trifluoro-3-oxobu ETHYL ETHOXYMETHYLENE-3-OXO-4,4,4-TRIFLUOROBUTYRATE Ethyl ethoxymethylene-3-oxo-4,4,4-trifluoro-butyrate ETHYL 2-(ETHOXYMETHYLENE)-4,4,4-TRIFLUOROACETOACETATE Ethyl 2-(Ethoxymethylene)-4,4,4-Trifluoroacetoacetate ETHYL 2-(ETHOXYMETHYLENE)-4,4,4-TRIFLUORO-3-OXOBUTYRATE Ethyl 2-(ethoxymethylene)-4,4,4-trifluoro-3-oxobutyrate ethyl 2-(ethoxymethylidene)-4,4,4-trifluoro-3-oxobutanoate ethyl (2E)-2-(ethoxymethylene)-4,4,4-trifluoro-3-oxo-butanoate ethyl (2Z)-2-(ethoxymethylidene)-4,4,4-trifluoro-3-oxobutanoate ethyl 2-(ethoxymethylene)-4,4,4-trifluoro-3-oxobutyrate,mixture of cis and trans
CAS	571-55-1
EINECS	611-474-9
InChI	InChI=1/C9H11F3O4/c1-3-15-5-6(8(14)16-4-2)7(13)9(10,11)12/h5H,3-4H2,1-2H3/b6-5+
InChIKey	XNGGOXOLHQANRB-WAYWQWQTSA-N

Ethyl 2-(Ethoxymethylene)-4,4,4-Trifluoroacetoacetate - Physico-chemical Properties

Molecular Formula	C9H11F3O4
Molar Mass	240.18
Density	1.235g/mLat 25°C(lit.)
Boling Point	80-82°C1mm Hg(lit.)
Flash Point	220°F
Vapor Presure	0.181mmHg at 25°C
Appearance	clear liquid
Specific Gravity	1.239
Color	Light orange to Yellow to Green
Storage Condition	2-8°C
Refractive Index	n20/D 1.429(lit.)
MDL	MFCD02677683

Ethyl 2-(Ethoxymethylene)-4,4,4-Trifluoroacetoacetate - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S23 - Do not breathe vapour.
WGK Germany	3
HS Code	29171900
Hazard Class	IRRITANT

Ethyl 2-(Ethoxymethylene)-4,4,4-Trifluoroacetoacetate - Introduction

Ethyl 2-(ethoxymethylene)-4,4,4-trifluoro-3-oxobu, also known as ethyl 2-(ethoxymethylene)-4,4, 4-trifluoro-3-oxobutyrate, the chemical formula is C8H7F3O4. It is an organic compound with the following properties:

1. Appearance: It is a colorless liquid with a special smell.

2. solubility: soluble in most organic solvents, such as ethanol, ether and dimethyl sulfoxide.

3. Melting point: Its melting point range is -40°C to -36°C.

4. Boiling point: Its boiling point is 100°C to 102°C.

ethyl ethyl 2-(ethoxymethylene)-4,4, 4-trifluororo-3-oxobu (EEOT) is commonly used as a reagent and intermediate, and has certain applications in organic synthesis. Here are some common uses:

1. synthetic drugs: EEOT can be used to synthesize certain drugs, such as acetylcholinesterase inhibitors and cholinergic receptor agonists.

2. Materials Science: EEOT can be used to prepare polymer materials, such as polyurethane and polyester.

3. Surfactant: EEOT has a low surface tension and can be used as a surfactant and emulsifier.

EEOT is prepared by the condensation reaction of ethoxyethylene ether and 2-fluoroethanone under alkaline conditions. During the preparation process, attention should be paid to safe operation, avoid contact with skin and eyes, and maintain good ventilation conditions. When handling or storing EEOT, high temperatures and sources of ignition should be avoided to prevent its decomposition or dangerous reactions.

Last Update：2024-04-09 21:21:28